منابع مشابه
Lymphoid malignancies ARNT unstoppable
(ARNT; also known as hypoxia inducible factor 1-β) is a member of the basic-helix-loop-helix-Per/ARNT/Sim (bHLH-PAS) family of transcription factors. ARNT is a common binding partner in this family and predominantly heterodimerizes with HIF-1α, or the aryl hydrocarbon receptor (AHR), and aids in the recognition of their respective DNA binding sequences [1]. The AHR has been recognized for decad...
متن کاملThe Role of Exosomes in Myeloid and Lymphoid Blood Malignancies: A Systematic Review Article
Background and Aim: Blood malignancies, one of the most common cancers in the world, cause a large number of deaths each year. Many inherited and acquired factors are involved in the development of this disease. Exosomes are a very small model of cells that are secreted by most cells in the body under physiological and pathological conditions. On the other hand, they have found a special place ...
متن کامل13q deletions in lymphoid malignancies.
Previous studies have indicated that a candidate tumor suppressor gene resides telomeric of the RB1 gene at 13q14, a region that is commonly deleted in B-cell chronic lymphocytic leukemia (B-CLL). In this study, we have evaluated the frequency and minimal region of overlap for 13q deletions in malignant cells from various lymphoid neoplasms. We observed losses at 13q14 in 33/75 (44%) B-CLL case...
متن کاملReovirus therapy of lymphoid malignancies.
Reoviruses infect cells that manifest an activated Ras-signaling pathway, and have been shown to effectively destroy many different types of neoplastic cells, including those derived from brain, breast, colon, ovaries, and prostate. In this study, we investigated the reovirus as a potential therapeutic agent against lymphoid malignancies. A total of 9 lymphoid cell lines and 27 primary human ly...
متن کاملHepatitis C virus and lymphoid malignancies.
A candidate HCV receptor on the surface of B cells is CD81, a member of the B-cell signaling membrane complex that includes CD19 and CD21. It is of interest that the expression of CD81 is increased in CD5+ B cells, considering that the expansion of CD5+ B cells is the hallmark of HCV-induced lymphoid stimulation. The spectrum of HCV-related or -associated lymphoproliferative disorders is very w...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2011
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.100.1781